I may need a little more information from you because I'm
a little unclear what you are wanting to do from the description.
I'm guessing you have multiple email accounts with different domains (like
email@example.com and firstname.lastname@example.org)
and you want to have your email program sort them out to different folders
according to the email account.
This is all possible, but it depends on the email program
you are using. One email client that supports these features is
Outlook Express (Free with Internet Explorer). You will have to
identify each email account and make rules for all incoming
messages. So when a message comes in for email@example.com
it gets sorted to the 'abc' folder and when a message comes in for firstname.lastname@example.org
it will get placed in the 'xyz' folder. Also, if you respond any of
these messages, they will be 'from' the correct email address that
it came to.